HGH 10IU

Research Polypeptide Hormone for Metabolic & Growth Studies

Recombinant Human Growth Hormone (rHGH), also known as Somatropin, is a 22 kDa polypeptide hormone consisting of 191 amino acids in a single chain with two intramolecular disulfide bonds. Produced via recombinant DNA technology, this research-grade hormone is identical in structure to endogenous pituitary growth hormone. In laboratory settings, rHGH serves as a critical tool for investigating the complex effects of growth hormone on somatic growth, protein synthesis, lipid metabolism, carbohydrate metabolism, and connective tissue function. Supplied as a lyophilized powder standardized to 10 International Units (IU) per vial (approximately 3.33mg), this preparation is intended strictly for controlled, non-human laboratory research to explore GH/IGF-1 axis signaling, tissue growth mechanisms, metabolic regulation, and age-related physiological changes in experimental models.

Complete Research Kit Contents & Verification

Each research order provides a complete experimental package designed for laboratory consistency, protocol standardization, and data integrity in growth and metabolic research:

• Primary Research Compound: 10 sterile glass vials containing 10IU (approximately 3.33mg) of lyophilized recombinant human growth hormone powder per vial. Potency is calibrated against the WHO International Standard.

• Reconstitution Solution: 30ml vial of sterile Bacteriostatic Water (0.9% Benzyl Alcohol), essential for creating stable hormone solutions for experimental use. Note: Some researchers prefer sterile water for certain assays to avoid benzyl alcohol interference.

• Laboratory Administration Tools: Pack of sterile syringes (including 1ml insulin syringes for precise measurement and 3ml syringes for reconstitution) with various gauges appropriate for different research applications.

• Sterilization Supplies: Individually wrapped alcohol prep swabs to maintain aseptic technique during vial handling and reconstitution.

• Research Protocol Documentation:

  • Dosing Schedule: Standardized administration protocol for common research models focusing on growth studies, metabolic regulation, tissue repair, and aging research.

  • Usage Instructions: Comprehensive guide covering gentle reconstitution techniques (to prevent aggregation), storage conditions (2-8°C after reconstitution, avoid freezing), handling safety, and experimental best practices for in-vivo endocrine/metabolic research.

• Quality Verification: Certificate of Analysis (CoA) provided with each batch, detailing:

  • Potency Verification (10IU ±10% by bioassay)

  • Purity Analysis (>98% by RP-HPLC and SEC-HPLC)

  • Identity Confirmation (Amino Acid Analysis & Peptide Mapping)

  • Related Proteins & Dimers/Aggregates (<2%)

  • Sterility Testing Results (Membrane Filtration)

  • Endotoxin Levels (<1.0 EU/IU)

  • Host Cell Protein/DNA Residuals

  • Isoform Distribution (by IEF)

Research Applications & Scientific Utility

In a laboratory setting, rHGH enables investigation across multiple research domains in endocrinology, metabolism, and developmental biology. Primary applications include studying the GH/IGF-1 axis and its effects on tissue growth, researching anabolic effects on protein synthesis and nitrogen retention, investigating metabolic effects on lipolysis, glucose metabolism, and insulin sensitivity, exploring connective tissue and bone growth/cartilage formation, and modeling age-related decline in hormone secretion. Researchers utilize this hormone to explore pulsatile vs. continuous delivery effects, tissue-specific responses, interaction with other endocrine systems, and potential therapeutic mechanisms in controlled experimental models. The included documentation supports standardized application to ensure reproducible results in growth and metabolic research.

Laboratory Handling & Safety Protocol

• Storage: Store unopened lyophilized rHGH vials at 2-8°C (refrigerated). Do not freeze. After reconstitution with bacteriostatic water, solutions are typically stable for 14-28 days when refrigerated at 2-8°C. For critical assays, many researchers prepare fresh solutions daily.

• Reconstitution: Must be performed gently under sterile laboratory conditions. Direct the stream of diluent against the glass wall, not onto the powder cake. Swirl gently to dissolve—do not shake, as vigorous agitation can denature the protein and cause aggregation.

• Laboratory Safety: Standard personal protective equipment (PPE) including lab coat, nitrile gloves, and safety glasses must be worn. Follow institutional biosafety level (BSL) guidelines for handling recombinant biological reagents.

• Documentation: The provided CoA must be retained as part of the research record for quality assurance and publication purposes. Note the exact IU to mg conversion (3IU ≈ 1mg) in experimental documentation.

⚠️ Critical Compliance & Intended Use Disclaimer:

THIS PRODUCT IS SOLD FOR RESEARCH USE ONLY (RUO). NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

1. Intended Use: Recombinant Human Growth Hormone is supplied as a biochemical reagent for laboratory research purposes only. It is intended for use by qualified researchers in controlled settings studying endocrinology, metabolism, and growth biology. The included “dosing schedule” refers to standardized research model administration protocols only.

2. Not for Human Consumption: Under no circumstances is this product intended for administration to humans or animals. It is not a drug, anti-aging treatment, performance enhancer, or bodybuilding supplement. The provided syringes and supplies are for laboratory measurement and transfer only.

3. Regulatory Status: This product has not been evaluated or approved by the FDA or any other global health authority for the diagnosis, cure, mitigation, treatment, or prevention of any disease or condition. While somatropin is available as a prescription drug for specific indications, THIS SPECIFIC PRODUCT IS NOT THAT DRUG.

4. Resale Prohibition: The buyer agrees not to resell, repackage, or represent this product for any application other than its intended research use.

5. Researcher Responsibility: It is the sole responsibility of the purchasing individual/institution to ensure compliance with all local, state, federal, and international regulations regarding the possession, use, and disposal of research hormones and laboratory supplies. rHGH is a Schedule III controlled substance in many jurisdictions with severe penalties for unauthorized distribution or use.