Ipamorelin 5mg

Selective Growth Hormone Secretagogue for Pulsatile Release Research

Ipamorelin is a synthetic pentapeptide (sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH₂) belonging to the growth hormone-releasing peptide (GHRP) class, specifically engineered as a selective agonist of the ghrelin/growth hormone secretagogue receptor (GHSR-1a). Its key research distinction lies in its ability to stimulate a physiological, pulsatile release of growth hormone from the pituitary with high specificity, having minimal to no effect on the secretion of cortisol, prolactin, ACTH, or other pituitary hormones, and lacking the strong ghrelin-like appetite stimulation associated with other GHRPs. Supplied as an acetate salt for enhanced stability, this lyophilized peptide is intended strictly for controlled, non-human laboratory research investigating the mechanisms of selective GH secretion, the GH/IGF-1 axis regulation, and the effects of pulsatile versus continuous GH patterns in experimental models.

Complete Research Kit Contents & Verification

Each research order provides a complete experimental package designed for precise endocrinology research:

• Primary Research Compound: 10 sterile glass vials containing 5mg of lyophilized Ipamorelin Acetate peptide powder per vial.

• Reconstitution Solution: 30ml vial of sterile Bacteriostatic Water (0.9% Benzyl Alcohol), essential for creating stable peptide solutions for experimental use.

• Laboratory Administration Tools: Pack of sterile 1ml insulin syringes (29G x 1/2″) for precise measurement and transfer in accordance with research protocols.

• Sterilization Supplies: Individually wrapped alcohol prep swabs to maintain aseptic technique during vial handling and reconstitution.

• Research Protocol Documentation:

  • Dosing Schedule: Standardized administration protocol for research models focusing on pulsatile GH secretion studies, receptor selectivity assays, and aging/endocrine research.

  • Usage Instructions: Comprehensive guide covering reconstitution math, storage conditions (-20°C recommended), handling safety, and experimental design considerations for timing-dependent pulsatility studies.

• Quality Verification: Certificate of Analysis (CoA) provided with each batch, detailing:

  • Purity Analysis (>98% by HPLC)

  • Amino Acid Sequence & Modifications Verified (Mass Spectrometry)

    • Confirmation of Aib (Aminoisobutyric acid) at position 1

    • Confirmation of D-2-Nal (D-2-Naphthylalanine) at position 3

  • Molecular Weight: 711.86 Da (Free Base) / 771.9 Da (Acetate Salt – approximate)

  • Sterility Testing Results

  • Endotoxin Levels (<10 EU/mg)

  • Residual Solvent Analysis

  • Salt Form Confirmation (Acetate)

  • Net Peptide Content

Research Applications & Scientific Utility

In a laboratory setting, Ipamorelin enables precise investigation into selective growth hormone secretagogue pathways. Primary research applications include studying the physiology of pulsatile versus continuous GH secretion and its differential effects on tissues, researching the selectivity of GHSR-1a activation without cross-activity with other pituitary receptors, investigating age-related decline in GH pulsatility and potential interventional models, exploring metabolic effects of GH in the absence of confounding cortisol or prolactin release, and serving as a comparator in studies against less selective GHRPs (like GHRP-2, GHRP-6) or ghrelin itself. Its clean profile makes it an ideal tool for isolating the effects of GH secretion in complex experimental systems.

Laboratory Handling & Safety Protocol

• Storage: Store unopened lyophilized peptide vials at -20°C or below. Ipamorelin is relatively stable, but consistent cold storage ensures long-term integrity. Reconstituted solutions should be aliquoted and stored at -20°C and used promptly for time-course experiments.

• Reconstitution: Must be performed under sterile laboratory conditions using the provided bacteriostatic water. The peptide dissolves readily.

• Laboratory Safety: Standard personal protective equipment (PPE) including lab coat, nitrile gloves, and safety glasses must be worn. Follow institutional biosafety guidelines.

• Timing Considerations: For research on pulsatility, precise timing of administration relative to sample collection is critical. Researchers should design protocols with this key pharmacological property in mind.

⚠️ Critical Compliance & Intended Use Disclaimer:

THIS PRODUCT IS SOLD FOR RESEARCH USE ONLY (RUO). NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

1. Intended Use: Ipamorelin is supplied as a biochemical reagent for laboratory research purposes only. It is intended for use by qualified researchers in controlled settings studying endocrinology and the growth hormone axis. The included “dosing schedule” refers to standardized research model administration protocols only.

2. Not for Human Consumption: Under no circumstances is this product intended for administration to humans or animals. It is not an anti-aging therapy, performance enhancer, or bodybuilding supplement. The provided syringes and supplies are for laboratory measurement and transfer only.

3. Regulatory Status: This product has not been evaluated or approved by the FDA or any other global health authority for any therapeutic use.

4. Selectivity Context: The marketing of selectivity is for research differentiation purposes only (e.g., vs. other GHRPs in an experimental design) and does not imply safety or approval for any use.

5. Researcher Responsibility: It is the sole responsibility of the purchasing individual/institution to ensure compliance with all regulations regarding the possession, use, and disposal of research peptides and to use this product only for legitimate, non-human research.