{"id":591,"date":"2025-12-28T18:48:28","date_gmt":"2025-12-28T18:48:28","guid":{"rendered":"https:\/\/www.zenpeptidesgreymarket.com\/?post_type=product&p=591"},"modified":"2025-12-28T18:48:28","modified_gmt":"2025-12-28T18:48:28","slug":"nad-500mg","status":"publish","type":"product","link":"https:\/\/www.zenpeptidesgreymarket.com\/?product=nad-500mg","title":{"rendered":"NAD+ 500mg"},"content":{"rendered":"

Essential Redox Cofactor for Cellular Metabolism & Longevity Research<\/strong><\/h3>\n

Nicotinamide Adenine Dinucleotide (NAD+) is a critical, ubiquitous coenzyme present in all living cells, playing a central role in cellular metabolism as a principal electron carrier in redox reactions. In its oxidized form (NAD+), it serves as a crucial co-substrate for key enzymes including sirtuins (class III histone deacetylases), poly(ADP-ribose) polymerases (PARPs), and CD38\/157 ectoenzymes, linking its bioavailability directly to fundamental processes of energy metabolism, DNA repair, circadian rhythm regulation, and cellular stress response. Research-grade NAD+ is supplied as a high-purity, lyophilized or crystalline powder for controlled laboratory investigation into age-related NAD+ depletion, mitochondrial dysfunction, and interventions targeting the NAD+\/NADH ratio. This compound is intended strictly for in-vitro and non-human in-vivo research to elucidate biochemical pathways governing cellular aging, metabolic disease, and neuroprotection.<\/p>\n

Complete Research Kit Contents & Verification<\/strong><\/h3>\n

Each research order provides a comprehensive experimental package designed for sensitive biochemical research:<\/p>\n

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  • \n

    Primary Research Compound:<\/strong>\u00a010 sterile glass vials containing 500mg of high-purity \u03b2-NAD+ (disodium salt, typically) powder per vial.<\/p>\n<\/li>\n

  • \n

    Reconstitution Solution:<\/strong>\u00a030ml vial of sterile 0.9% Sodium Chloride (Saline) or specialized NAD+ stabilization buffer.\u00a0Note:<\/strong>\u00a0Bacteriostatic water is not recommended for NAD+ due to potential degradation from benzyl alcohol; sterile saline is provided instead.<\/p>\n<\/li>\n

  • \n

    Laboratory Administration Tools:<\/strong>\u00a0Pack of sterile syringes (1ml for precise dosing and 3ml for reconstitution) and alcohol swabs.<\/p>\n<\/li>\n

  • \n

    Research Protocol Documentation:<\/strong><\/p>\n

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    • \n

      Dosing Schedule:<\/strong>\u00a0Protocol for research models, including common concentrations for cell culture supplementation (e.g., 1-10mM) and considerations for in-vivo research.<\/p>\n<\/li>\n

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      Usage Instructions:<\/strong>\u00a0Critical guide covering\u00a0light-sensitive and temperature-sensitive handling<\/strong>, rapid reconstitution with cold solution to minimize degradation, short-term storage guidelines (aliquot and store at -80\u00b0C), and compatibility with various assay systems.<\/p>\n<\/li>\n<\/ul>\n<\/li>\n

    • \n

      Quality Verification:<\/strong>\u00a0Certificate of Analysis (CoA)<\/strong>\u00a0provided with each batch, detailing:<\/p>\n

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        Purity Analysis (>98% by HPLC, assessing NAD+ vs. degradation products NADH, ADP-ribose, nicotinamide)<\/p>\n<\/li>\n

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        Identity Confirmation (UV-Vis Spectroscopy – characteristic peak at ~259nm, A250\/A260 ratio)<\/p>\n<\/li>\n

      • \n

        Potency\/Content Assay (Enzymatic cycling assay)<\/p>\n<\/li>\n

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        Sterility Testing (for solutions intended for in-vivo research)<\/p>\n<\/li>\n

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        Endotoxin Levels (<0.1 EU\/mg for sensitive cell work)<\/p>\n<\/li>\n

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        Water Content (for lyophilized form)<\/p>\n<\/li>\n

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        pH of Reconstituted Solution<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n

        Research Applications & Scientific Utility<\/strong><\/h3>\n

        In a laboratory setting, research-grade NAD+ enables investigation into foundational biochemical pathways. Primary applications include:<\/p>\n

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        • \n

          Sirtuin Research:<\/strong>\u00a0Studying activation of SIRT1-7 and their roles in deacetylation, metabolism, and stress resistance.<\/p>\n<\/li>\n

        • \n

          Mitochondrial Function:<\/strong>\u00a0Investigating electron transport chain efficiency, ATP production, and mitochondrial biogenesis.<\/p>\n<\/li>\n

        • \n

          Aging & Senescence Models:<\/strong>\u00a0Researching NAD+ depletion as a hallmark of aging and testing NAD+ repletion strategies.<\/p>\n<\/li>\n

        • \n

          DNA Repair Studies:<\/strong>\u00a0Examining PARP-mediated DNA repair mechanisms in response to genotoxic stress.<\/p>\n<\/li>\n

        • \n

          Metabolic Disease Research:<\/strong>\u00a0Exploring NAD+ metabolism in models of obesity, diabetes, and fatty liver disease.<\/p>\n<\/li>\n

        • \n

          Neurodegeneration Research:<\/strong>\u00a0Investigating the role of NAD+ in neuronal health and models of Alzheimer’s\/Parkinson’s disease.<\/p>\n<\/li>\n<\/ul>\n

          Laboratory Handling & Safety Protocol \u2013 CRITICAL<\/strong><\/h3>\n
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          • \n

            Storage:<\/strong>\u00a0Store unopened vials at\u00a0-20\u00b0C or ideally -80\u00b0C<\/strong>, protected from light and moisture.\u00a0Stability is paramount.<\/strong>\u00a0Aliquot reconstituted solution immediately and store at -80\u00b0C. Avoid repeated freeze-thaw cycles.<\/p>\n<\/li>\n

          • \n

            Reconstitution:<\/strong>\u00a0Use ice-cold, sterile saline or specified buffer. Work quickly on ice. Gently swirl to dissolve\u2014do not vortex. The solution is highly unstable at room temperature and neutral pH.<\/p>\n<\/li>\n

          • \n

            Light Sensitivity:<\/strong>\u00a0Perform all handling under low-light conditions. Use amber vials or wrap in foil for storage.<\/p>\n<\/li>\n

          • \n

            Laboratory Safety:<\/strong>\u00a0Standard PPE (lab coat, nitrile gloves, safety glasses) is required. NAD+ is not highly toxic but should be treated as a potent biochemical.<\/p>\n<\/li>\n<\/ul>\n

            \u26a0\ufe0f Critical Compliance & Intended Use Disclaimer:<\/strong><\/p>\n

            THIS PRODUCT IS SOLD FOR RESEARCH USE ONLY (RUO). NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.<\/strong><\/p>\n

              \n
            1. \n

              Intended Use:<\/strong>\u00a0NAD+ is supplied as a biochemical reagent for laboratory research purposes only. It is intended for use by qualified researchers in controlled in-vitro or non-human in-vivo settings.<\/p>\n<\/li>\n

            2. \n

              Not for Human Consumption:<\/strong>\u00a0Under no circumstances is this product intended for intravenous, subcutaneous, or any form of human administration. It is not a drug, anti-aging supplement, or IV therapy ingredient.<\/p>\n<\/li>\n

            3. \n

              Regulatory Status:<\/strong>\u00a0This product has not been evaluated or approved by the FDA or any other health authority for the diagnosis, treatment, cure, or prevention of any disease.<\/p>\n<\/li>\n

            4. \n

              Stability Disclaimer:<\/strong>\u00a0Due to the inherent instability of NAD+, the seller guarantees purity and quantity at time of shipment only. Proper handling by the researcher is essential for experimental validity.<\/p>\n<\/li>\n

            5. \n

              Researcher Responsibility:<\/strong>\u00a0The purchaser assumes all responsibility for compliance with regulations and for the safe, ethical, and appropriate use of this research compound.<\/p>\n<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

              YOUR ORDER COMES WITH;<\/strong><\/p>\n

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              • \n

                10 VIALS x 500mg<\/strong>\u00a0of High-Purity NAD+ Research Compound<\/p>\n<\/li>\n

              • \n

                FREE:<\/strong>\u00a0Sterile Saline Solution (30ml) for reconstitution, Sterile Syringes (1ml & 3ml), and Alcohol Swabs<\/p>\n<\/li>\n

              • \n

                DOSING SCHEDULE:<\/strong>\u00a0Comprehensive laboratory administration and dosing protocol for cell culture and research models<\/p>\n<\/li>\n

              • \n

                USAGE INSTRUCTIONS:<\/strong>\u00a0Detailed reconstitution guide, stability parameters, and handling procedures for this sensitive coenzyme<\/p>\n<\/li>\n

              • \n

                A COPY OF LAB RESULTS:<\/strong>\u00a0Certificate of Analysis (CoA) confirming purity, identity, and sterility<\/p>\n<\/li>\n<\/ul>\n

                NAD+ (\u03b2-Nicotinamide Adenine Dinucleotide) is an essential pyridine nucleotide coenzyme supplied for research into cellular respiration, sirtuin enzyme function, genomic stability, and mitochondrial health. This complete research kit includes all necessary components for standardized experimental studies in biochemistry and cell biology.<\/p>\n","protected":false},"featured_media":520,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[24],"product_tag":[],"class_list":["post-591","product","type-product","status-publish","has-post-thumbnail","product_cat-peptides","first","instock","shipping-taxable","purchasable","product-type-simple"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.zenpeptidesgreymarket.com\/index.php?rest_route=\/wp\/v2\/product\/591","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.zenpeptidesgreymarket.com\/index.php?rest_route=\/wp\/v2\/product"}],"about":[{"href":"https:\/\/www.zenpeptidesgreymarket.com\/index.php?rest_route=\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/www.zenpeptidesgreymarket.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=591"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.zenpeptidesgreymarket.com\/index.php?rest_route=\/wp\/v2\/media\/520"}],"wp:attachment":[{"href":"https:\/\/www.zenpeptidesgreymarket.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=591"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/www.zenpeptidesgreymarket.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_brand&post=591"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/www.zenpeptidesgreymarket.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_cat&post=591"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/www.zenpeptidesgreymarket.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_tag&post=591"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}