HCG 5000IU

Research Glycoprotein Hormone for Endocrine & Reproductive Studies

Human Chorionic Gonadotropin (hCG) is a complex glycoprotein hormone composed of 237 amino acids with an alpha subunit identical to luteinizing hormone (LH), follicle-stimulating hormone (FSH), and thyroid-stimulating hormone (TSH), and a unique beta subunit that confers biological specificity. In research settings, hCG serves as a direct analog for LH due to its action on the same receptor (LHCGR), making it an invaluable tool for studying steroidogenesis, gonadal function, and reproductive physiology. Supplied as a lyophilized powder standardized to 5000 International Units (IU) per vial, this preparation is intended strictly for controlled, non-human laboratory research to investigate hormonal signaling pathways, testicular Leydig cell stimulation, ovarian follicular maturation, and corpus luteum maintenance in experimental models.

Complete Research Kit Contents & Verification

Each research order provides a complete experimental package designed for laboratory consistency, protocol standardization, and data integrity in endocrine research:

• Primary Research Compound: 10 sterile glass vials containing 5000IU of lyophilized hCG powder per vial. Potency is calibrated against the WHO International Standard.

• Reconstitution Solution: 30ml vial of sterile Bacteriostatic Water (0.9% Benzyl Alcohol), essential for creating stable hormone solutions for experimental use.

• Laboratory Administration Tools: Pack of sterile syringes (including 1ml for precise low-dose measurement and 3ml for reconstitution) with various gauges (29G, 25G) appropriate for different research applications.

• Sterilization Supplies: Individually wrapped alcohol prep swabs to maintain aseptic technique during vial handling and reconstitution.

• Research Protocol Documentation:

  • Dosing Schedule: Standardized administration protocol for common research models focusing on endocrine stimulation, steroidogenesis studies, and reproductive system investigations.

  • Usage Instructions: Comprehensive guide covering reconstitution math (note: delicate glycoprotein requiring gentle handling), storage conditions (2-8°C after reconstitution), handling safety, and experimental best practices for in-vivo endocrine research.

• Quality Verification: Certificate of Analysis (CoA) provided with each batch, detailing:

  • Potency Verification (5000IU ±10% by bioassay)

  • Purity Analysis (by SEC-HPLC and SDS-PAGE)

  • Subunit Confirmation (Alpha & Beta subunit presence)

  • Sterility Testing Results (Membrane Filtration)

  • Endotoxin Levels (<1.0 EU/IU)

  • pH and Osmolality of Reconstituted Solution

  • Residual Moisture Content (Lyophilization Quality)

Research Applications & Scientific Utility

In a laboratory setting, hCG enables investigation across multiple research domains in endocrinology and reproductive biology. Primary applications include studying testicular steroidogenesis and Leydig cell function in male models, researching ovarian follicular development, ovulation induction, and corpus luteum support in female models, investigating hormonal feedback mechanisms in the hypothalamic-pituitary-gonadal (HPG) axis, exploring off-target effects in cancer research (some cancers express LHCGR), and modeling pregnancy-related hormonal changes. Researchers utilize this glycoprotein to explore dose-response relationships in steroid production, timing effects in ovulation studies, and interactions with other hormonal systems in controlled experimental models. The included documentation supports standardized application to ensure reproducible results in endocrine research.

Laboratory Handling & Safety Protocol

• Storage: Store unopened lyophilized hCG vials at 2-8°C (refrigerated). Do not freeze. After reconstitution, solutions are stable for 30-60 days when refrigerated at 2-8°C. For long-term storage, aliquot and freeze at -20°C, though some activity loss may occur.

• Reconstitution: Must be performed gently under sterile laboratory conditions using the provided bacteriostatic water. Swirl gently to dissolve—do not shake vigorously, as this may denature the glycoprotein structure.

• Laboratory Safety: Standard personal protective equipment (PPE) including lab coat, nitrile gloves, and safety glasses must be worn. Follow institutional biosafety level (BSL) guidelines for handling biological reagents. hCG is a biological substance; treat with appropriate caution.

• Documentation: The provided CoA must be retained as part of the research record for quality assurance and publication purposes. Potency in IU is critical for experimental reproducibility.

⚠️ Critical Compliance & Intended Use Disclaimer:

THIS PRODUCT IS SOLD FOR RESEARCH USE ONLY (RUO). NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

1. Intended Use: hCG is supplied as a biochemical reagent for laboratory research purposes only. It is intended for use by qualified researchers in controlled settings studying endocrinology and reproductive biology. The included “dosing schedule” refers to standardized research model administration protocols only.

2. Not for Human Consumption: Under no circumstances is this product intended for administration to humans or animals. It is not a drug, fertility treatment, performance enhancer, or weight loss aid. The provided syringes and supplies are for laboratory measurement and transfer only.

3. Regulatory Status: This product has not been evaluated or approved by the FDA or any other global health authority for the diagnosis, cure, mitigation, treatment, or prevention of any disease or condition. While hCG is available as a prescription drug, THIS SPECIFIC PRODUCT IS NOT THAT DRUG.

4. Resale Prohibition: The buyer agrees not to resell, repackage, or represent this product for any application other than its intended research use.

5. Researcher Responsibility: It is the sole responsibility of the purchasing individual/institution to ensure compliance with all local, state, federal, and international regulations regarding the possession, use, and disposal of research hormones and laboratory supplies. hCG is a potent biological agent with significant potential for misuse.